The Elusive Functions of Proteoglycans
نویسندگان
چکیده
منابع مشابه
The Elusive Functions of Proteoglycans
chains, can make purification challenging and structural analysis painful. Their ability to bind scores of growth factors, growth factor-binding proteins, extracellular proteases, protease inhibitors, extracellular matrix molecules, and other proteins takes the concept of molecular promiscuity to new heights. On top of this, they seem always to be underfoot, showing up on plasma membranes in hu...
متن کاملThe Elusive Functions of Proteoglycans: In Vivo Veritas
chains, can make purification challenging and structural analysis painful. Their ability to bind scores of growth factors, growth factor-binding proteins, extracellular proteases, protease inhibitors, extracellular matrix molecules, and other proteins takes the concept of molecular promiscuity to new heights. On top of this, they seem always to be underfoot, showing up on plasma membranes in hu...
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This issue of Seminars in Cell and Developmental Biology contains a number of articles reviewing the cellular functions of proteoglycans. Proteoglycans are proteins, substituted with glycosaminoglycans (GAGs), that generally either decorate the cell membrane or fill the extracellular space. GAGs are linear polysaccharides consisting of a repeating disaccharide, generally of an acetylated amino ...
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Deoxyribonucleic acid methylation is a long known epigenetic mark involved in many biological processes and the 'readers' of this mark belong to several distinct protein families that 'read' and 'translate' the methylation mark into a function. Methyl-CpG binding domain proteins belong to one of these families that are associated with transcriptional activation/repression, regulation of chromat...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2000
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.148.2.227